Insight
In pharmaceutical manufacturing, the goal is to always improve the efficiency, safety, and quality of drug production. Traditional methods like freeze drying have served us well, but they come with limitations such as high energy costs and lengthy processing times.
Electrostatic Drying (ESD) is a ground-breaking technology setting new standards, particularly in the production of temperature-sensitive active pharmaceutical ingredients (APIs).
A recent study by Purdue University researchers, published in collaboration with Fluid Air, highlights the substantial benefits of using ESD for protein-based pharmaceuticals.
Unlike conventional high-temperature processes that can degrade sensitive materials, ESD operates effectively at low temperatures. This not only preserves the stability and potency of heat-sensitive APIs but also enhances the product's shelf life significantly.
Why Electrostatic Drying?
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Lower Temperature Processing: Reduces the risk of thermal degradation, preserving the integrity and efficacy of APIs.
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Increased Efficiency: Streamlines production by eliminating the need for secondary processes like particle size modification while reducing energy consumption.
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Superior Product Quality: Achieves higher encapsulation efficiency, ensuring better protection and delivery of APIs.
ESD leverages an electrostatic charge to separate the solvent from the active ingredients during the drying process. This method offers more versatility for particle engineering and leads to superior morphology, crucial for the development and consistent manufacturing of dosage forms.
As the pharmaceutical industry continues to focus on innovative solutions to meet global health challenges, technologies like ESD are at the forefront, enabling faster and more effective drug production. This not only aids in quicker market introduction but also significantly reduces manufacturing costs and environmental impact.
Whether you're involved in R&D or production, the implications of integrating electrostatic drying into your processes could be transformative.
Let's embrace these advancements to not just keep pace but lead in the delivery of next-generation pharmaceuticals.
Interested in learning more?
For further information or to explore how electrostatic spray drying can benefit your production processes, feel free to reach out to Jimi Kjærsgaard Pettersson, Expertise Director NIRAS.